Síntese Direta de 4-organoilsulfenil-7-cloroquinolinas a partir de 4,7-dicloroquinolinas e Tióis.

Abstract

In this study, 4,7-dichloroquinoline was used as a starting material in reactions with different thiols for the synthesis of several 4-organylsulfenyl-7-chloroquinolines 3a-l using DMSO (dimethylsulfoxide) as solvent, in the absence of additives and/or catalysts. This simple and general method provides products in moderate to excellent yields (52-98%) with regioselectivity.