Síntese de (Z)-Tioeninos Utilizando Solventes Recicláveis

Abstract

In this work, PEG-400 and glycerol were successfully used as recyclable solvents for the synthesis of several organylthioenynes in good to excellent yields 39 to 98% and high selectivity. This easy, general and simple method, consists in the addition of thiols to 1,4-diorganyl-1,3-butadiynes, using solid supported catalyst KF/Al2O3, furnishes the corresponding vinyl sulfides preferentially with Z configuration (Scheme 1). The catalytic system can be reused up to three times without previous treatment with comparable activity.