Fatores prognósticos de doença cardiovascular em pacientes com aterosclerose manifesta no município de Pelotas/RS

Abstract

Cardiovascular diseases, besides representing the leading cause of death in Brazil and worldwide, can lead to chronic conditions. Secondary prevention of patients with this comorbidity becomes important, and the study of prognostic factors helps in such conduct. The aim of this work was to evaluate prognostic factors of cardiovascular diseases and to investigate possible associations between them, in a sample of patients with established atherosclerosis disease, in Pelotas/RS. Cross-sectionals studies, nestled to a randomized clinical trial, were performed, with data of the collaborating site of Pelotas/RS. Clinical, anthropometric, biochemistry, sociodemographic, alimentary and health-related quality of life variables were collected. Statistical analyzes were carried out in Graph Pad® e Stata®. The majority of the sample was men, elderly, from economic level C, studied until elementary school, was former or current smoker and had overweight, coronary artery disease, hypertension, dyslipidemia and familiar history of cardiovascular diseases. About alimentary consumption (n=74), classified according to the degree of processing, the group that most contributed to caloric consumptio was unprocessed/minimally processed foods (50.9%), followed by ultra-processed (35.1%), processed (11.1%) and processed culinary ingredients (2.9%). Overweight and being current/former smoker were positively associated to the pontuation of metabolic syndrome, with an increase of 0.64 and 0.48 points, respectivetly (n=82). Regarding health-related quality of life (n=70), the score of physical health domains was lower than the mental health (p<0.0001). Body mass index and waist circumference were negatively associated to health-related quality of life, whereas the consumption of dietary fiber, potassium and magnesium presented a positive association. In the analysed sample, alimentary consumption across the degree of processing foods was elevated, since the consumption of processed/ultra-processed foods was almost the same of unprocessed/minimally processed foods. Dietary fiber, potassium and magnesium were positively associated to health-related quality of life. On the other hand, high values of waist circumference and body mass index were negatively associated to health-related quality of life. Moreover, elevated body mass index (overweight) and tobacco use were identified as risk factors that increase the pontuation of metabolic syndrome. Thus, the secondary prevention of patients analysed must contemplate interventions to an healthier lifestyle, mainly focused to an adequate diet and to the maintenance of a proper weigh.