Síntese de 3-Selanilimidazo[1,2-a]piridinas promovida por ácidos benzenosselenínicos como fonte de selênio eletrofílico

Abstract

In the present work, a method for obtaining 3-selanylimidazo[1,2-a]pyridines was developed. Benzeneseleninic acids used as an electrophilic source of stable and easy to handle selenium, containing donor and withdrawing groups, reacted with different imidazo[1,2-a]pyridines at 110 ºC for 3 hours, using dimethylformamide as solvent. In total, 33 compounds (3a-ag) could be synthesized, 17 of which were unpublished, where they were obtained in good to excellent yields.