Avaliação in vitro de uma combinação de antimicrobianos alternativos sobre a inibição do crescimento de bactérias patogênicas

Abstract

This study evaluated in vitro the antibacterial effect of the product Viligen®, composed of microencapsulated sodium butyrate, mannanoligosaccharides, and organic zinc. The bacterial growth reduction capacity was analyzed in the absence and presence of the compound at concentrations of 500 ppm, 1000 ppm, 1500 ppm and 2000 ppm, at different pHs (4.5, 5.0, 5.5 and 6.0). The bacteria evaluated were the gram-negatives negative Escherichia coli, Salmonella Typhimurium and Salmonella Heidelberg, and the gram-positives Staphylococcus aureus, Staphylococcus epidermidis and Clostridium sp. The results demonstrated the presence of antibacterial effects in all bacteria analyzed at pH 4.5, regardless of the concentration of the compound. These in vitro findings suggest that the compound can reduce the concentration of pathogens in the food bolus in the upper portion of the gastrointestinal tract of broilers, thereby decreasing bacterial challenge and preventing intestinal disorders and infections.