Alterações laboratoriais e sua relação com a terapia instituída em felinos diagnosticados com neoplasias atendidos no HCV – UFPel

Abstract

The increase in the feline population as a pet is a worldwide trend, which leads to the search for specialized veterinary care and monitoring for the species. Feline neoplasms play a relevant role among the main causes of morbidity and mortality, in addition to spontaneous neoplasms in domestic animals serving as a model for studies and treatments in comparative oncology of neoplasms in humans. The analysis of hematological and biochemical parameters is widely used in veterinary medicine for the establishment of diagnosis, prognosis and monitoring of cancer treatment. Although neoplasms are important, there are few studies that specifically cover the hematological, pathological and therapeutic parameters of neoplasms in felines. Thus, the present study aimed to conduct a 5-year retrospective study of the tests requested at the Clinical Pathology Laboratory of the Hospital de Clínicas Veterinária (Veterinary College/Federal University of Pelotas), to verify the data of the felines and the treatment received in the main neoplasms. Considering the objectives, the thesis is composed of two scientific works. The first work is a retrospective study of the tests requested in diagnosed cases of neoplasms in felines. The main hematological alterations were related to the two most common types found in the study (Squamous Cell Carcinoma - SCC and Lymphoma) and were related to cytopenias, with thrombocytopenia, leukopenia and anemia observed in most patients. The second article refers to the report of a rare case of ocular follicular lymphoma associated with viral coinfection by calicivirus, FIV and FeLV in a feline. From this work and considering the high frequency of malignant tumors in felines, it is concluded that early diagnosis is important, as well as hematological evaluations that can identify the severity of the condition, assist in the establishment of diagnosis, prognosis and monitoring of treatment, and the complete blood count should be used before surgeries and chemotherapy. The data obtained may help in future studies on the use of these parameters in feline neoplasms.