Síntese de teluroalquinos mediada por K3PO4 e DMSO

Abstract

In the present work, a simple and efficient methodology is described by reactions between terminal alkynes 1a-m and diorganyl ditellurides 2a-e in the presence of potassium phosphate (K3PO4) and DMSO, in order to obtain different alkynyltellurides 3a-qAfter determination of the best reaction condition, this method was applied to different terminal alkynes 1a-m and diorganyl ditellurides 2a-e, using electron donating and withdrawing substituents. In both substrates, it was possible to vary the aryl and alkyl groups, obtaining the products of interest in short reaction times and in yields ranging from 30 to 93%. This methodology, differently from those already reported in literature, has the advantage of not using metallic catalysts, but only a weak base is used.